[Drug Name] 20% Tilmicosin Premix
Tilmicosin genus-specific semi-synthetic macrolide antibiotic,
tylosin antibacterial and similar sensitive gram-positive bacteria
Staphylococcus aureus (including penicillin-resistant
Staphylococcus aureus), Streptococcus pneumoniae , Streptococcus,
Bacillus anthracis, swine erysipelas bacteria, Listeria
monocytogenes, Clostridium, emphysema, gangrene and other
Clostridium. Sensitive Gram-negative bacteria Haemophilus, pleurisy, meningitis,
and other Pasteurella, Mycoplasma also effective. For the activity
of pleurisy Actinobacillus, Pasteurella multocida and Mycoplasma
livestock, this drug is stronger than tylosin. 95% of the hemolytic
Pasteurella strains sensitive to the chemicals.
Oral absorption fast, characterized by strong tissue penetration,
large volume of distribution (>2L/kg). High concentrations in the lung, the half-life of up to 1-2 days,
effective blood concentration was maintained for a long time.
[Drug Interaction] (1) Combined use with epinephrine, can increase
the death of pigs.
(2) And other macrolides, lincosamides due to the same targets, can’t used at the same time.
(3) Combined with - lactams were antagonistic.
[Indication] For the treatment of swine pleuropneumonia, lung
disease and swine asthma.
[Usage and Dosage] Mixed: per 1000kg of feed, pigs 1000-2000g. Stay
for 15 days.
[Side Effects] (1) The product of animal toxicity is mainly the
cardiovascular system, can cause tachycardia and contractility.
(2) Many animals often appear dose-dependent gastrointestinal disorders
after taking orally, such as vomiting, diarrhea and intestinal
pain, etc.), it can be caused by of smooth muscle stimulation.
[Attention] Only for the treatment, tilmicosin irritating to the
eyes, it can cause allergic reactions, avoid direct contact.
[Withdrawal Period] Pigs 14 days.
[Storage] Shading, Sealing
[Valid Date] 2 years.
[Product Standard] 《China Veterinary Pharmacopoeia》 (2010 Edition I)