Product Name: Progesterone
Product Categories: MI;FINISHED
(Others);Intermediates & Fine
Chemicals;Pharmaceuticals;Intracellular receptor;Steroid and
Hormone;API;ENDOMETRIN;Plant extract;Pharma material;Inhibitors
Mol File: 57-83-0.mol
MP 128-132 °C(lit.)
alpha 186 º (c=1, ethanol)
refractive index 182 ° (C=2, Dioxane)
storage temp. Store at RT
solubility H2O: 25 mg/mL, may be clear to slightly hazy
Water Solubility <0.1 g/100 mL at 19 ºC
Stability: Stable. Incompatible with strong oxidizing agents.
Hazard Codes Xn,T,F
Risk Statements 40-45-62-36-20/21/22-11
Safety Statements 36/37-45-53-16
WGK Germany 3
Description of Progesterone :
Progesterone is a hormone released by luteal cells in the ovaries
which contains 21 Carbon Atoms. Progesterone is also a crucial
metabolic intermediate in the production of other endogenous
steroids. There are two crystal forms of progesterone, that are
type-α and type-β, the two types have similar physiological
activity. Type-α is precipitated from dilute ethanol as
orthorhombic white prismatic crystal, while type-β is orthorhombic
white needle crystal, they are both insoluble in water, but soluble
in ethanol, ethyl ether, chloroform, acetone, dioxane and
concentrated sulfuric acid.
Progesterone can be released by the ovary, placenta and adrenal
cortex. Its physiological function mainly manifests in promoting
estrogen treated over thicken lining of the uterus to continue the
development, proliferation and thickening and hypertrophy, soften
and secretion of mucus in order to make good condition for
implantation of the fertilized egg. After the implantation, early
stage survival and development of fertilized egg is also under the
control of the high progesterone release. As a result, progesterone
is a very important hormone in the female reproductive system, and
it is also an important intermediate in the biosynthesis of steroid
hormones. All steroid hormone releasable glands can produce
progesterone, but only ovarian and placenta can release
progesterone as the main hormone. Ovarian will release large amount
of progesterone in the luteal phase after ovulation by granulose
luteal cells, so progesterone is also named as progestin.
Progesterone will decrease in result of corpus luteum atrophy. For
normal women, placenta will becomes the main organ maintain
progesterone after 8 to 9 weeks of pregnancy, accompany with the
ovary releasing until the end of pregnancy.
The main physiological effects of progesterone:
1. Progesterone can maintain the female animal pregnancy, and cause
a series of physiological changes, such as inhibition of female
2. Progesterone has the power to promote the thickening of the
lining of the uterus, promote the bending of the gland and to
increase secretion function.
3. Progesterone can inhibit the peristalsis of the uterus, and
contribute to the cervix contraction, secretion of mucus, etc..
These physiological changes provide suitable environment for the
operation, growth and development of early embryos, as well as the
continued growth of the fetus.
4. Small amount of progesterone is also used in combination with
the hormone estrogen to promote female estrus. The synergy between
progesterone and prolactin can promote the development of mammary
5. Progesterone is involved in the feedback regulation of the
hypothalamus and anterior pituitary, which makes the balance of the
animal reproductive hormones. In vivo, progesterone content of all
sorts of livestock follicular phase is below 1 ng / ml, while in
bovine corpus luteum period is approximately 4 ng / ml, pregnancy
period is about 18 ng / ml.
Usage And Synthesis:
Formerly biochemical study shows that progesterone modulates action
as progestogens, clinical for the treatment of habitual abortion,
dysmenorrhea, amenorrhea and other symptoms. One of progesterone's
most important functions is as hormone drugs, to promote and
maintain the uterine changes in the early stage of pregnancy, used
in habitual abortion, irregular menstruation, etc.. In addition,
progesterone also behaves as steroid hormone drug as well as
progestogens, which is used in treatment of threatened abortion.
In the 40's, only chemical method can be used to monitor the
excretion of pregnanediol which is the metabolism of progesterone
in the urine of 24h, this could reflect the level of progesterone
Started from the 50's, progesterone levels in plasma could be
determined not only by chemical methods, but also by biological
methods and gas chromatography.
At the end of the 60's, radionuclides and protein competition were
developed to determine progesterone.
In the 70's, the radiation immune assay and the radiation receptor
method have appeared, which greatly improved the sensitivity and
accuracy of the assay. When determination of progesterone in blood
has been widely used, the determination of urinary progesterone has
lost its importance. Normal value of follicular phase in urine was
1mg/24h, and in the corpus phase was 2-8mg/24h. Changes of
progesterone levels in women of childbearing age can reflect the
different stages of the menstrual cycle. For pregnant women, blood
progesterone continued rising, which is not coincidence with the
normal cycle. For the person of congenital 17α-hydroxylase
deficiency syndrome, there is abnormal ratio of progesterone to
17α-Hydroxy progesterone, that is progesterone ascending while
17α-Hydroxy progesterone decreasing.
Preparation Products And Raw materials:
Raw materials Cyclohexanone-->16-Dehydropregnenolone
Preparation Products Deoxycorticosterone acetate
Semi-finished Inject/Oral steroids:
|Tri Tren 180||180mg/ml|
|Tri Test 300||300mg/ml|
|Tri Deca 300||300mg/ml|
|Test Blend 450||450mg/ml|
|Test Blend 500||500mg/ml|
|Nandro Test 225||225mg/ml|
|Cut Depot 400||400mg/ml|
|Tren Test 225||225mg/ml|
|Nandro Test Depot 450||450mg/ml|
|Equi Test 450||450mg/ml|
|Rip Cut 175||175mg/ml|
Please contact us via :
|How to Proceed Your Orders?|
You confirm all details, and offer us purchasing order.
We send the detail price of our product and offer the suitable
shipping method for reference.
You confirm the order and pay money 100% in advance and send us the
detailed contacting information, including contacting
person/company, address, mobile number,ZIP code and your special
Parcel would be arranged within 12 hours upon receipt of your
Photos would be offered to tell apart the products .
Tracking number :
Send by EMS, the tracking number is availabe within 12 hours . The
info would be trackable that day or 1 day later.
If send by HKEMS or other express,the tracking number would be
provided next day. And this does not mean the info is trackable
that day. It would be released on internet 2 or 3 days later . The
reason why is that parcel should be shipped to Hongkong from
forwarder then wait for the flight .
You sign for the parcel , deliveried.
We offer after-sales service after you receive parcel.
Any question, email me, I am sherry.
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Dear sir ,
Good days to you!
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|More products information, please contact sherry.Here's her
Shanghai ShuCan Industrial Co.,Ltd.
Room1301,No.28,19NorthFisheries Road, Changning
Lead time:Within 12 hours upon the receipt of payment.
Delivery time:3-7working days.
Pay term:Western Union,Bank Transfer,Bitcoins,Money Gram
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Your early response would be highly appreciated!So,dont hesitate
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